Market Executive Summary

REPORT HIGHLIGHT
The hemophilia market is estimated to represent a global market of USD 10.23 billion by 2017 with growth rate of 5.3%.

Market Dynamics

Over the eight years to 2017, revenue for the hemophilia industry is anticipated trend higher. Increasing neonatal population is expected to drive the hemophilia diagnosis demand globally. The World Population Meter stated that more than 88.0 billion newborns were reported in 2017 resulting in about 250 births per minute. Of which, approximately 2.8 million infants died within the first month, due to lack of skilled care and proper screening of the babies. The World Health Organization (WHO) also stated that around 2.6 million children died in their first month of life across the globe, which is 7,000 newborn deaths every day. In addition, strong product pipeline will further stimulate the industry growth to great extent over the future period. For example, N9-GP, Concizumab, N8-GP, and Recombinant factor VIIa are some of the bleeding disorder therapeutics under clinical investigations by Novo Nordisk. Despite the industry pipeline increasing, some potential threats exist which will likely to hinder growth prospects going forward. Factors such as high treatment cost coupled with low acceptance of advanced technologies are posing a potential threat to the market.

Types Takeaway

In terms of types, the market is categorized into A, B, C, and other types. Type A accounted for the highest share of the total market. In 2017, the segment recorded 6.8 billion and is expected to dominate the global market over the forecast period. This type is acquired due to the deficiency of clotting factor VIII, which is an anti-hemophilic factor (AHF). According to the National Hemophilia Foundation (NHF), 1 in 5,000 male population affect with type A disorder, which makes it four times more common compared to the type B. As per the Hemophilia News Today, around 4,000 to 5,000 males are affected with type A disease worldwide. Markets besides hemophilia A, B & C is expected to generate the remaining 5.0% of market revenue in 2017.

Treatment Takeaway

The treatment segment is divided into On-demand and Prophylaxis. Inpatient with mild to severe hemophilia, treatment is being given at the time when bleeding occurs which is termed as on-demand therapy. The on-demand treatment industry is in the mature phase and is projected to grow with a significant growth rate over the foreseeable future. Depending upon therapy, the market is segmented as Immune Tolerance Induction (ITI), Replacement, and Gene therapy. Replacement therapy captures a major chunk of the global revenue. This method is performed through the infusion of factor VIII and IX concentrates to prevent bleeding. On contrary, gene therapy is considered to be the lowest revenue generating segment, generated less than 1% revenue in 2017. Most of the gene therapies for hemophilia treatment are under clinical studies and likely attract greater demand during the future period.

Key Vendor Takeaway

Companies namely, Novo Nordisk, Bayer AG, Pfizer, Inc., Baxalta, and Biogen are profiled. In light of more players entering in this market. the degree of competition has intensified over a couple of years. Competition is based on the development of new therapeutics and co-pay programs.

For example, Grifols provide co-pay programs such as ALPHANATE Copay Program and AlphaNine SD Copay card for this bleeding disorder treatment with an unlimited monetary limit. In addition, companies are engaged in donation activities with government organizations. For instance, in 2017, the World Federation of Hemophilia collected 1.5 million units of anti-hemophilic agents from CSL Behring as a donation on World Hemophilia Day.

The market size and forecast for each segment and sub-segments has been considered as below:

Historical Year ? 2017 ? 2021
Base Year ? 2021
Estimated Year ? 2022
Projected Year ? 2028
TARGET AUDIENCE

Traders, Distributors, and Suppliers
Manufacturers
Hospitals
Government and Regional Agencies and Research Organizations
Consultants
Distributors
SCOPE OF THE REPORT

The scope of this report covers the market by its major segments, which include as follows:

MARKET, BY TYPES

Hemophilia A
Hemophilia B
Hemophilia C
Others
MARKET, BY TREATMENT

On-demand
Prophylaxis
MARKET, BY THERAPY

Immune Tolerance Induction (ITI) therapy
Replacement therapy
Gene therapy
MARKET, BY REGION

North America
U.S.
Canada
Europe
Germany
France
Rest of Europe
Asia Pacific
India
China
Rest of APAC
Rest of the World
Middle East and Africa
Latin America