Top drug delivery methods in future that will stun you!
Posted on 10-January-2020
Top drug delivery methods in future that will stun you!
Over the past few years, a conspicuous evolution of drug delivery strategies has been seen, involving both modifications & advanced methods as per prospects. The current drug delivery systems (DDS) are starting with various routes of drug formulations, introducing new biotechnology-based applications, drug administration to researching new methods to the system challenging the 21st century.
Drug delivery is an expansive field of research inclusive of the commonly used methods like steady, controlled & targeted drug delivery. Although efficient & proper drug delivery plays a crucial role in treatment which is ultimately a big challenge in the medical field.
Innovation in drug delivery is a big-league part of the product life process. From the non-oral delivery of biologics to advances in nanotechnology, the future of drug delivery is sound. An overview of the recent top drug delivery methods will be presented in this article examined by the DCAT value chain insights (VCI). These advanced methods of drug delivery in pharma-field will stun you!
1. Nanotechnology
Nanotechnology opens up new avenues for developing nano-systems to orally deliver drugs difficult to administer drugs. The ability to cross the intestinal barrier has been a major problem in oral medications & the use of nano-systems proved to be the finest solution over that problem. Nano-systems can also penetrate the blood-brain barrier which will help the field to find a relevant drug-delivery method to reach the brain. Another recent development in nanotechnology-based drug delivery is the nanoformulation of a superhydrophobic anticancer drug for cancer.
2. Microchips
A physician-friendly device! Microchips implants are self-contained hermetically-sealed drug-device to implant & remove with wireless control features. They are Biotech's electronic device made up of arrays having a capacity to store therapeutic drug doses. For a period of a month to a year, the doses can be stored safely. Also, it has a programming system which is programmed to release drug on a pre-determined scheduled.
3. 3-D printing
3D printing is the first technology for manufacturing the first drug-product approved by the US food & drug administration. The technology has launched tablets for oral suspension that disintegrate in the mouth with a sip of liquid. The ZipDose technology originated from the 3-D printing technology that forms objects in layers using the aqueous field to stitch together the multiple layers. ZipDose technology enables the delivery of high-dose medications in a rapidly disintegrating form.
4. Gene delivery
A proprietary non-viral vector platform for gene delivery to mucosal cells lining the gut is being developed by Takeda Pharmaceutical Company Ltd & enGen Inc. They aim to discover, develop & commercialize therapies for especially gastrointestinal (GI) diseases using enGene's "Gene pill" gene delivery platform. A platform for oral delivery of antibodies!
5. Oral delivery of peptides
Numerous new approaches have been led for developing devices for the administration of peptides. Perhaps, many challenges need to be overcome for giving a reliable peptide delivery vehicle to the future of drug-delivery systems. If these challenges are overcome, the drug-delivery devices hold therapeutic promise for diseases where patients need to take frequent injections.
